Why is Clonal Evolution Still a Sterile Theory?

Despite major revelations in the science of cancer, a classic theory of how it develops—clonal evolution—has remained a perplexing vestige of ‘sterile’ cancer biology.  Arguing against the sterility of tumors, the last decade of research has revealed metabolically...
Microbiome Therapeutics Try a Lighter Touch

Microbiome Therapeutics Try a Lighter Touch

The revelation that our commensal bacteria play important roles in health and disease has turned the microbiome into one of the most active frontiers of biomedicine. Yet our efforts to turn our “inner bugs” into drugs have long been limited to investigational fecal...